|Includes a list of characters, actors and production crew members whose first names are Jeffrey.|
- Geoffrey Radcliffe - Also known as the Invisible Man; the main character from The Invisible Man Returns.
- Jeff Barton - William Shatner's character from the "Cold Hands, Warm Heart" episode of The Outer Limits.
- Jeff Austin - Actor who appeared in episodes of Babylon 5, Star Trek: Deep Space Nine, Star Trek: Voyager and The X-Files.
- Jeffrey Combs - Actor from Re-Animator and episodes of The 4400, The Twilight Zone, Star Trek: Deep Space Nine and Star Trek: Enterprise.